- 64 Scopus Citations
- 34 PubMed Citations
ORCID
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Full Name
Matboli, Marwa
Scopus Author ID
WOS ID
Biography
Name:
Marwa Matboli Sayed Mohamed
Position:
1. Acting head of Medical Biochemistry Department and Molecular Biology, Faculty of Medicine, Modern university for technology and information from July 2019 till present.
2. Associate professor Of Medical Biochemistry Department and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
3. Member of Basic Research Unit, Medical Research Unit, Ain Shams Faculty of Medicine from 2016 till present
4. Coordinator Of Biomedical Research Department, Armed Forces College of medicine from 2016 till 2017
5. Coordinator Of Medical Biochemistry Department and Molecular Biology, Armed Forces College of medicine from 2016 till 2017
Specialty:
Medical Biochemistry Department and Molecular Biology
Scopus ID
https://www.scopus.com/authid/detail.uri?authorId=55920873100
http://orcid.org/0000-0002-6852-3954
Google Scholar ID
https://scholar.google.com.eg/citations?user=clJGV9UAAAAJ&hl=ar
Researchgate ID
https://www.researchgate.net/account.AccountSettings.html
Subspecialty/ special interest:
Activities
1- Sharing as a member in the teamwork for biomarker discovery in cancer leaded by Prof. Dr. Sanaa Eissa Mohammed, Faculty of Medicine, Ain Shams University.
2-Sharing as a member in the teamwork for bionanotechnology research leaded by Prof. Dr. Hassan Mohamed Elazzazy, Science and Technology Research Center, American University in Cairo.
Grants
1- Sharing as CO-Principal investigator in a project entitled; Development of nanoassay for early detection of Bladder Cancer. Ain Shams University project 2014-2015
2-Sharing as CO-Principal investigator in a project entitled; Development of nanoassay for early detection of Diabetic nephropathy. RSGT 6653, STDF 2015-2016
3-Sharing as Principal investigator in a project entitled; Targeting miRNA by medicinal plants to modulate autophagy signaling pathway: A new therapeutic approach of diabetic nephropathy, RSGT 2751, STDF 2015-2016
4- Sharing as CO-Principal investigator in a project entitled; Target-based therapeutic approach towards diabetes mellitus by modifying autophagy Signaling, Special Targeted Call: Health (Call 3), “TC/3/Health/2017, STDF.
5- Sharing as CO-Principal investigator in a project entitled; Exosomes as divine messengers in Breast cancer: Implications for inter-cellular communication, therapy and biomarker development. Basic & Applied Research, STDF 2017
6-Sharing as CO- Principal investigator in a project entitled; Gene editing of lncRNA-associated ceRNAs network: in treating type 2 DM. ASRT JESOR 2017 ,ID:2017-2961.
7- Sharing as CO- Principal investigator in a project entitled; implementation of comprehensive molecular & next generation sequencing- based genetic testing strategy to improve and prevent fatal outcomes of coronary artery disease related to familial hypercholesterolemia. ASRT JESOR 2017 ,ID:2017-
8- Sharing as CO-Principal investigator in a project entitled; Evbaluation of renal damage after PCNL and ESWEL using novel RNA markers, STDF young researcher 2019
9- Sharing as CO-Principal investigator in a project entitled; Targeted approach for Gut Microbiome Manipulation, novel key player in Type 2 Diabetes mellitus Management. ASRT JESOR 2019
10- Sharing as Principal investigator in a project entitled; Evaluating the Clinical Significance of the Nourin-Based RNA Network for the Early Detection of Acute Myocardial Infarction (AMI) Patients. Armed Forced College of Medicine and Nour Heart Diagnostics &Theraputics, USA, 2017.
11- Sharing as a member in FP7 project entitled (Proteomic analysis in breast screening study) during the period between (2010-2012).
Thesis Supervision
Master Thesis
1. Evaluation of non coding RNA expression in acute kidney injury(2018)
2. Evaluation of Minichromosome maintenance complex component 5 (MCM5) and Forkhead box m (FOXm) genes expression in primary breast cancer (2013).
3. Evaluation of microRNA expression in Obesity (2014)
4. Evaluation of long non-coding RNA expression in hepatocellular carcinoma (2014)
5. The discovery of putative urine marker for detection of diabetic nephropathy by integrative mining of public miRNA databases (2014)
6. Evaluation of long non-coding RNA and Autophagy related gene association in Hepatocellular carcinoma
7. Assessment of Non-Coding RNA Expression as a Potential Stem Cell Biomarker in Breast Cancer
8. Identification of Novel Biomarkers that reflect Mitophagy-Apoptosis Interplay within Hepatocellular Carcinoma
9. Integrative Pipeline to Identify Potential Long Non-Coding RNA-Associated Competing Endogenous RNA and Its Implication in Hepatocellular Carcinoma Cells
10. Phytochemical extracts: A Target based therapeutic approach for diabetes mellitus via autophagy signaling Modulation in rat model
PHD supervision
1. The Effect of Ibuprofen Arginate on a Murine Model of Diabetic Neuropathy & study of the possible mechanisms (2013)
2. Evaluation of MicroRNA-210 (miRNA-210) and Protein tyrosine phosphatase, non-receptor type 2 (PTPN2) in Pre-eclampsia (2015)
3. Epigenetic control of autophagy receptors in diabetic nephropathy (2015)
4. Efficacy of phytochemical extracts of rosemary in Head and neck squamous cell carcinoma cell line (2015)
5. Study of the Effect of Resveratrol and Lycopene on Laryngeal Carcinoma Cell Line (2015)
6. Evaluation of diagnostic and therapeutic Roles of Exosomes in Hepatocellular Carcinoma
7. Evaluation of circular RNA network expression in Hepatocellular carcinoma
8. CLINICAL SIGNIFICANCE OF EXOSOMES AND AUTOPHAGY IN HEPATOCELLULAR CARCINOMA
9. The Clinical Relevance of Non-Coding RNAs in Colorectal Cancer.
10. The Potential Effect of Sodium Butyrate (a Histone deacetylaseinhibitor) on Hepatic Autophagy in Carbon Tetrachloride and Concanavalin A induced Liver Fibrosis in BALB/c mice.
11. Emerging ROLE OF EXOSOMES based therapeutics in management of Hepatocellular carcinoma
12. Evaluation of expression of circulating nucleic acid in traumatic spinal cord injuries
13. Assessment of the efficacy of gene editing tool as a promising strategy in management of insulin resistance in type 2 diabetes mellitus
14. Targeting non-coding RNAs with Gene Editing Tool system in hepatocellular carcinoma cell lines
15. Assessment of Cardiprotective Effect of phytochemical extract in ischemic heart is mediated via induction of stem cell proliferation
16. Efficacy of fucoxanthin on head and neck squamous cell carcinoma cell line
17. Transcriptome spectral analysis using hyperspectral imaging for hepatocellular carcinoma detection
18. Immune modulation in management of colorectal cancer
19. Impact of gut microbiota on the epigenetic regulation of Nonalcoholic Steatohepatitis in animal model
20. Exploring the rule of hedgehog signaling in management of non-alcoholic steatohepatitis
Publications
1. Amany Hasanin, Eman Habib, Nesserin El Gayar, Marwa Matboli. Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study. World Journal of Hepatology March 2021
2. Aboughaleb, I.H., Matboli, M., Shawky, S.M., El-Sharkawy, Y.H. Integration of transcriptomes analysis with spectral signature of total RNA for generation of affordable remote sensing of Hepatocellular carcinoma in serum clinical specimens. Heliyon, 2021, 7(3), e06388
3. Matboli, M., Saad, M., Hasanin, A.H., ...Bekhet, M.M., Eissa, S.New insight into the role of isorhamnetin as a regulator of insulin signaling pathway in type 2 diabetes mellitus rat model: Molecular and computational approach. Biomedicine and Pharmacotherapy, 2021, 135, 111176.
4. Hossam, N., Matboli, M., Shehata, H.H., ...Hassan, M.K., Eissa, S.Toll-like receptor immune modulatory role in personalized management of colorectal cancer, review of literature. Expert Review of Precision Medicine and Drug Development, 2020, 5(6), pp. 455–468.
5. Matboli, M., Ibrahim, D., Hasanin, A.H., ...Afifi, A.M., Eissa, S.Epigenetic modulation of autophagy genes linked to diabetic nephropathy by administration of isorhamnetin in Type 2 diabetes mellitus rats Epigenomics, 2021, 13(3), pp. 187–202
6. Maha Saad, Mansour Mohamed Kabash, Aymn El Sayed Shafei …,Marwa Matboli. Microbiome in GIT Cancers: New Frontiers in Personalized Medicine – A Review of Literature. Journal of surgical oncology 2020
1. Salah SMM, Matboli M, Nasser HE, Abdelnaiem IA, Shafei AE, El-Asmer MF.Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury.Genomics. 2020 Sep;112(5):3315-3321. doi: 10.1016/j.ygeno.2020.06.018. Epub 2020 Jun 11.PMID: 32535070
2. Ali HS, Boshra MS, El Meteini MS, Shafei AE, Matboli M. lncRNA- RP11-156p1.3, novel diagnostic and therapeutic targeting via CRISPR/Cas9 editing in hepatocellular carcinoma.Genomics. 2020 Sep;112(5):3306-3314. doi: 10.1016/j.ygeno.2020.06.020. Epub 2020 Jun 13.PMID: 32544548
3. Marwa Matboli ,Eman K Habib, Reham Hussein Mohamed, Amany H Hasanin. Pentoxifylline alleviated cardiac injury via modulating the cardiac expression of lncRNA-00654-miR-133a-SOX5 mRNA in the rat model of ischemia-reperfusion. Biomedicine and pharmacotherapy 2020. DOI: 10.1016/j.biopha.2020.109842
1. Rashed WM, Hamza MM, Matboli M, Salem SI. MicroRNA as a prognostic biomarker for survival in childhood acute lymphoblastic leukemia: a systematic review.Cancer Metastasis Rev. 2019 Dec 5. doi: 10.1007/s10555-019-09826-0. [Epub ahead of print] Review.PMID: 31807971.
2. AH Hasanin, M Matboli, HS Seleem. Hesperidin suppressed hepatic precancerous lesions via modulation of exophagy in rats. Journal of cellular biochemistry 121 (2), 1295-1306.
3. Mariam Ezzat Labib, Marwa Matboli*, Hanaa El-Tayeb Nasser, Ahmed Hassan Fawzi El-Tawdi, Eman K. Habib, Randa Ali-LabibEXTRACELLULAR VESICLES miR-1298 and lncRNA-RP11-583F2.2 EXPRESSION in HEPATOCELLULAR CARCINOMA. Current Genomics.DOI : 10.2174/1389202920666191210111849
4. Marwa Matboli*, Ayman E. Shafei, Sara H.A. Agwa, Sherif Sammir Elzahy, Ahmed K. Anwar, Amr R. Mansour, Ahmed I. Gaber, Ali E.A. Said, Paula Lwis, Marwa Hamdy. Identification of novel molecular network expression in Acute Myocardial Infarction. Current Genomics Volume 20 , Issue 5 , 2019.DOI : 10.2174/1389202920666190820142043
5. El-Shal AS, Matboli M, Abdelaziz AM, Morsy AA, Abdelbary EH. Role of a novel circulatory RNA-based biomarker panel expression in ovarian cancer.IUBMB Life. 2019 Dec;71(12):2031-2047. doi: 10.1002/iub.2153. Epub 2019 Sep 13.PMID: 31520466.
6. Matboli M, Shafei AE, Ali MA, El-Din Ahmed TS, Naser M, Abdel-Rahman T, Anber N, Ali M. Role of extracellular LncRNA-SNHG14/miRNA-3940-5p/NAP12 mRNA in colorectal cancer.Arch Physiol Biochem. 2019 Aug 9:1-7. doi: 10.1080/13813455.2019.1650070. [Epub ahead of print].PMID: 31397210.
7. Salem AM, Ragheb AS, Hegazy MGA, Matboli M, Eissa S. Caffeic Acid Modulates miR-636 Expression in Diabetic Nephropathy Rats.Indian J Clin Biochem. 2019 Jul;34(3):296-303. doi: 10.1007/s12291-018-0743-0. Epub 2018 Feb 26.PMID: 31391719
8. Ihab S. Abd El-Hamid *, Yara Y. Mouselhy, Marwa M. El-Shafei, Marwa M. Sayed, Aly F. Mohamed, Doaa B. Farag. COX-2 Docking Structural Analysis with Phytochemical Extracts of Rosemary: A Possible Cytotoxicity on Head and Neck Squamous Cell Carcinoma Cell Line (HEp-2). Anti-Cancer Agents in Medicinal Chemistry. DOI : 10.2174/1871520619666190618121706
9. Habieb A, Matboli M, El-Tayeb H, El-Asmar F. Potential role of lncRNA-TSIX, miR-548-a-3p, and SOGA1 mRNA in the diagnosis of hepatocellular carcinoma. Mol Biol Rep. 2019 Apr 19. doi: 10.1007/s11033-019-04810-x. [Epub ahead of print] Erratum in: Mol Biol Rep. 2019 May 2;PMID: 31004302
10. Matboli M, ElGwad AA, Hasanin AH, El-Tawdi A, Habib EK, Elmansy RA, Ibrahim D, Shehata H, Tash F.Pantoprazole attenuates tumorigenesis via inhibition of exosomal secretion in a rat model of hepatic precancerous lesion induced by diethylnitrosamine and 2-acetamidofluorene.J Cell Biochem. 2019 Apr 22. doi: 10.1002/jcb.28757.
11. Eissa S, Safwat M, Matboli M, Zaghloul A, El-Sawalhi M, Shaheen A.Measurement of Urinary Level of a Specific Competing endogenous RNA network (FOS and RCAN mRNA/ miR-324-5p, miR-4738-3p, /lncRNA miR-497-HG) Enables Diagnosis of Bladder Cancer.Urol Oncol. 2019 Apr;37(4):292.e19-292.e27. doi: 10.1016/j.urolonc.2018.12.024. Epub 2019 Jan 14. PMID: 30654976
12. Matboli M, Shafei AE,Ali MA, et al. circRNAs (hsa_circ_00156, hsa_circ000224, and hsa_circ _000520) are novel potential biomarkers in hepatocellular carcinoma. J Cell Biochem. 2018;1‐14.https://doi.org/10.1002/jcb.28045
13. Matboli M, Shafei AE,Ali MA, et al. Clinical significance of serum DRAM1 mRNA, ARSA mRNA, hsa‐miR‐2053 and lncRNA‐RP1‐86D1.3 axis expression in malignant pleural mesothelioma. J Cell Biochem. 2018;1‐9. https://doi.org/10.1002/jcb.27586
14. Samir N, Matboli M, El-Tayeb H, et al. Competing endogenous RNA network crosstalk reveals novel molecular markers I colorectalcancer.JCellBiochem.2018;119:6869–6881.https://doi.org/10.1002/jcb.26884
15. Abd El‐Gwad A, Matboli M, El‐Tawdi A, et al. Role of exosomal competing endogenous RNA in patients with hepatocellular carcinoma. J Cell Biochem. 2018;119:8600–8610.https://doi.org/10.1002/jcb.27109
16. Matboli M1, Shafei A2, Ali M2, Kamal KM3, Noah M3, Lewis P3, Habashy A3, Ehab M3, Gaber AI3, Abdelzaher Emerging role of nutrition and the non-coding landscape in type 2 diabetes mellitus: A review of literature. Gene. 2018 Oct 30;675:54-61. doi: 10.1016/j.gene.2018.06.082. Epub 2018 Jun 27.
17. Shafei A1, Matboli M1,2, Mostafa E1, Al Sannat S1, Abdelrahman M1, Lewis B1, Muhammad B1, Mohamed S2, Mostafa RM Stop eating plastic, molecular signaling of bisphenol A in breast cancer. Environ Sci Pollut Res Int. 2018 Aug;25(24):23624-23630. doi: 10.1007/s11356-018-2540-y. Epub 2018 Jun 29
18. Nossier AI, Abdelzaher H, Matboli M, Eissa S. Dual approach for the colorimetric determination of unamplified microRNAs by using citrate capped gold nanoparticles.Mikrochim Acta. 2018 Mar 22;185(4):236. doi: 10.1007/s00604-018-2767-9
19. Salem, A.M., Ragheb, A.S., Hegazy, M.G.A., Matboli, M., Eissa, S. Caffeic Acid Modulates miR-636 Expression in Diabetic Nephropathy Rats. 2018 Indian Journal of Clinical Biochemistry
20. Mahmoud A. Ali, Marwa Matboli, Nashwa El-Khazragy, Osama Saber, Sarah El-Nakeep, Hana M. Abdelzaher, Ayman El-Sayed Shafei, Randa Mostafa. Investigating miRNA-661 and ATG4-B mRNA expression as potential biomarkers for hepatocellular carcinoma. Biomarkers in Medicine, In Press
21. Marwa Matboli, Ayman E Shafei, Ahmed EM Azazy, Maged Reda, Nashwa El-Khazragy, Ahmed Aly Nagy, Mahmoud A. Ali, Mohamed Sobhi, Omar Abdel-Rahman. Clinical Evaluation of Circulating miR-548-3p and-20a Expression in Malignant Pleural Mesothelioma Patients. Biomarkers in Medicine, In Press
22. Marwa Matboli, Ahmed EM Azazy, SehamAdel, Miram M Bekhet, Sanaa Eissa. Evaluation of Urinary Autophagy Transcripts Expression in Diabetic Kidney Disease. Journal of Diabetes and Its Complications 2017.
23. Marwa Matboli , Ayman E Shafei , Hanan H Shehata ,Nesreen Nabil ,Nourhan Hossam , Ahmed EM Azazy , ,Ahmed HF.El-Tawdi , Omar Abdel-Rahman. Clinical Significance of miRNA-Autophagy Transcript Expression in Patients with Hepatocellular Carcinoma. Biomarkers in Medicine, In Press.
24. A Shafei, M Matboli, M Ali, Z Nagy, M Reda, M Salah, A Hamdy Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma. bioRxiv, 288381 2018
25. S Mohamed, M Matboli, AES Shafei, H Khalaf, M Ashraf, MS Riad. Non-coding RNAs as key player in stem cell proliferation and differentiation; Potential therapeutic strategies in spinal cord injuries. Journal of Medical 2017 Biotechnology 1 (1)
26. FM Tash, AM Abd-Elgawad, M Matboli, SM Shawky, HH Shehata. Clinico-pathological correlates of MCM5 and FOXM1 expression in primary breast cancer tissues J Pharma Pharma Sci 2016
27. Marwa Matboli, Sanaa Eissa, Doaa Ibrahim, Marwa G.A.Hegazy, Shalabia S. Imam, Eman K Habib. Caffeic Acid Attenuates Diabetic Kidney Disease via Modulation of Autophagy in a High-Fat Diet/Streptozotocin- Induced Diabetic Rat. Sci Rep. 2017 May 23;7(1):2263. doi: 10.1038/s41598-017-02320-z.PMID:28536471
28. Eissa, Sanaa, Marwa Matboli ,Nahla Awad, Yousif Kotb Identification and validation of a novel autophagy gene expression signature for human bladder cancer Patients. TUMOR Biology 2017
29. Mahmoud A Ali, Marwa Matboli, Marwa Tarek, Maged Reda, Kamal M Kamal, Mahmoud Nouh, Ahmed M Ashry, Ahmed Fath El-Bab, Hend A Mesalam, Ayman El-Sayed Shafei, and Omar Abdel-Rahman. Epigenetic regulation of immune checkpoints: another target for cancer immunotherapy? Immunotherapy, January 2017 ,Vol. 9, No. 1 , Pages 99-108 (doi: 10.2217/imt-2016-0111)
30. Adel S, Mansour A, Louka M, Matboli M, Elmekkawi SF, Swelam N. Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia. Gene. 2017 Jan 5;596:105-109. doi: 10.1016/j.gene.2016.10.014. Epub 2016 Oct 13.
31. GM El-Lithy, WM El-Bakly, M Matboli, HA Abd-Alkhalek MayHamza. Prophylactic L-arginine and ibuprofen delays the development of tactile allodynia and suppresses spinal miR-155 in a rat model of diabetic neuropathy.Translational Research 2016.
32. Eissa, Sanaa , Marwa Matboli, Rowaida Aboushahba, Miram M. Bekhet, Yasser Soliman. Urinary exosomal microRNA panel unravels novel biomarkers for diagnosis of type 2 diabetic kidney disease. Journal of Diabetes and Its Complications 2016, Volume 0 , Issue 0.
33. El-Tawdi AH, Matboli M, El-Nakeep S, Azazy AE, Abdel-Rahman OAhmed . Association of long noncoding RNA and c-JUN expression in hepatocellular carcinoma Expert Rev Gastroenterol Hepatol. 2016 May 23. [Epub ahead of print]
34. Matboli M, El-Nakeep S, Hossam N, Habieb A, Azazy AEM, Ebrahim AE, Nagy Z, Abdel-Rahman O. Exploring the role of molecular biomarkers as a potential weapon against gastric cancer: A review of the literature. World J Gastroenterol 2016; 22(26): 5896-5908 Available from: URL: http://www.wjgnet.com/1007-9327/full/v22/i26/5896.htm DOI: http://dx.doi.
org/10.3748/wjg.v22.i26.5896
35. Sanaa Eissa, Marwa Matboli, Miram M. Bekhet .Clinical verification of a novel urinary microRNA panel: 133b, -342 and -30 as biomarkers for diabetic nephropathy identified by bioinformatics analysis. Biomedicine & Pharmacotherapy, Volume 83, Issue null, Pages 92-99
36. Ahmed HF.El-Tawdi, Marwa Matboli, Hanan H Shehata, Tash FM, Nashwa El-Khazragy, Ahmed EM Azazy,Omar Abdel-Rahman. Evaluation of Circulatory RNA Based Biomarker Panel in Hepatocellular Carcinoma. Molecular Diagnosis & Therapy 2016. In press
37. MM Kamel, M Matboli, M Sallam, IF Montasser, AS Saad, AHF El-Tawdi. Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. Transl Res. 2016 Jan 7.
38. Eissa S, Marwa Matboli, Nada O.E. Essawy, Mahmod Shehta,Youssef M.Kotb. Rapid Detection of Urinary Long Non-Coding RNA Urothelial Carcinoma Associated One Using a PCR-Free Nanoparticle-Based Assay. Biomarkers J 2015.
39. Eissa S, Matboli M, Shawky SM, Essawy NO. Urine biomarkers of Schistosomiais and its associated bladder cancer. Expert review of anti-infective therapy j 2015.
40. S Eissa, M Matboli, A Sharawy, F El-Sharkawi. Prognostic and biological significance of microRNA-221 in breast cancer. Gene 574 (1), 163-167.
41. Eissa S, Matboli M, Hegazy MG, Kotb YM, Essawy NO. Evaluation of urinary microRNA panel in bladder cancer diagnosis: relation to bilharziasis. Transl Res. 2015 Jan 7. pii: S1931-5244(15)00003-1. doi: 10.1016/j.trsl.2014.12.008. [Epub ahead of print] PMID: 25620614
42. Eissa S, Matboli M, Shehata HH, Essawy NO.MicroRNA-10b and minichromosome maintenance complex component 5 gene as prognostic biomarkers in breast cancer. Tumour Biol. 2015 Jan 18. [Epub ahead of print].PMID: 25596707
43. S Eissa, M Matboli, NOE Essawy, YM Kotb. Integrative fun ctional genetic-epigenetic approach for selecting genes as urine biomarkers for bladder cancer diagnosis.Tumor Biology 36 (12), 9545-9552
44. Eissa S, Matboli M, Shehata HH. Breast tissue-based microRNA panel highlights microRNA-23a and selected target genes as putative biomarkers for breast cancer. Transl Res. 2015 Mar;165(3):417-27. doi: 10.1016/j.trsl.2014.10.001. Epub 2014 Oct 31.PMID: 25445205
45. Eissa S, Azzazy HM, Matboli M, Shawky SM, Said H, Anous FA. The prognostic value of histidine-rich glycoprotein RNA in breast tissue using unmodified gold nanoparticles assay. Appl Biochem Biotechnol. 2014 Sep;174(2):751-61. doi: 10.1007/s12010-014-1085-x. PMID: 25091325
46. Matboli M, Eissa S, Said H. Evaluation of histidine-rich glycoprotein tissue RNA and serum protein as novel markers for breast cancer. Med Oncol. 2014 Apr;31(4):897. doi: 10.1007/s12032-014-0897-4. Epub 2014 Feb 25.
47. Eissa S, Matboli M, Mansour A, Mohamed S, Awad N, Kotb YM. Evaluation of urinary HURP mRNA as a marker for detection of bladder cancer: relation to bilharziasis. Med Oncol. 2014 Feb;31(2):804. doi: 10.1007/s12032-013-0804-4. Epub 2013 Dec 28.
48. Eissa S, Shawky SM, Matboli M, Mohamed S, Azzazy HM. Direct detection of unamplified hepatoma upregulated protein RNA in urine using gold nanoparticles for bladder cancer diagnosis. Clin Biochem. 2014 Jan;47(1-2):104-10. doi: 10.1016/j.clinbiochem.2013.10.022. Epub 2013 Oct 29.
49. Matboli M, Eissa S. Integrated technologies in the post-genomic era for discovery of bladder cancer urinary markers. World J Clin Urol 2013 November 24; 2(3): 20-31 .ISSN 2219-2816 (online
50. Sanaa Eissa, Marwa Matboli, Randa Ali-Labib. Apoptosis Inhibitory Gene in Bladder Cancer Diagnosis: Molecular Screening for Bladder Cancer Project PI: Sanaa Eissa Ain Shams Faculty of Medicine ., 2/2012; LAP Lambert Academic Publishing AG & Co KG., ISBN: 9783846586266.
Patency
ELGEBALY SALWA AHMED, SAYED and MARWA MATBOLI .A Novel Autophagy-Related Nourin Gene-Based RNA Network as Early Biomarkers for Cardiac Patients. Grant US-10895572-B2 - Published 2021-01-19 Granted 2021-01-19 Priority 2018-06-18
Family: 6
1-
ELGEBALY SALWA AHMED, SAYED and MARWA MATBOLI . Application WO-2020148589-A1, EARLY BIOMARKERS FOR CARDIAC PATIENTS. Original Assignee :NOUR HEART INC .Legal status Granted
3-Rapid nanoassay for detection of miRNA in urine. ASERT 1631-2017.ID- 16252402
4- Transcriptome spectral analysis using hyperspectral imaging for hepatocellular carcinoma detection. ASERT 1561-2019.
Degrees:
1. MD in Medical Biochemistry and Molecular Biology ,November 2012
Thesis: Proteomic Analysis in Breast Screening Study
Grade: GPA:3.12
Faculty: Faculty of Medicine, Ain Shams University
2. Attached as academic visitor Sant George University of Central London during the period (2010-2012).
3. MSc in Medical Biochemistry, May 2009
Thesis: Detection of mRNA of Apoptosis Inhibition Gene in Urine of Bladder Cancer
Grade: Excellent
Faculty: Faculty of Medicine, Ain Shams University
3-M.B, B.ch in Medicine , December 2002
Grade: Excellent
Faculty: Faculty of Medicine, Ain Shams University
Training:
1. Computer Programs, Faculty of Computer and Bioinformatics, Ain Shams University 2004.
2. Effective Teaching in FLDP 2009
3. Student Assessment, Quality Assurance Unit , Faculty of Medicine ,Ain Shams University ,June 2010
4. How To make Scientific Research in Community Department, Ain Shams University ,2009.
5. Proteomic workshop and sample processing., Saint George University., London ,August ,2010.
6. Maldi/TOF mass spectrometer training and its application in biomarker ,Southampton University , August ,2010.
7. Proteomic analysis in biomarker discovery ,Clinical pathology Department ,Alexandria University ,February 2011.
8. Proteomic analaysis in breast cancer screening workshop .,Biomedical Academy of Athens , 2011.
9. Interactive education., Quality Assurance Unit , Faculty of Medicine ,Ain Shams University ,May 2011
10. Stem cell workshop, biochemistry department, Faculty of Medicine ,Cairo University ,May 2012.
11. Financial & Legal Aspects in College Work, Faculty & Leadership Development Center, Ain Shams University, September 2013
12. Local and international competitive research projects, Faculty & Leadership Development Center, Ain Shams University, August 2014.
13. Teaching methodology, Armed Force faculty of medicine,2014
14. Student Centered Learning in Medical Education, Armed Force faculty of medicine, August 2014
15. Problem-Based Learning in Medical Education, Armed Force faculty of medicine, March 2015
16. Technology in Teaching, Faculty & Leadership Development Center, Ain Shams University, August 2015
17. Constructing Clinical Scenarios in Medical Education, Armed Forces College of Medicine, August 2015.
18. Practical & Online electronic courses, Medical Biochemistry Department, Ain Shams University, 2015-2016
19. Research methodology. Armed Force faculty of medicine, May 2016
20. Researcher Connect Course, British Council in Egypt, February 2017
21. Communicative Presentation Skills by The British University in Egypt, Armed Forces College of Medicine, April 2017.
22. Navigating peer-review workshop, Armed Forces College of Medicine, May 2017.
23. Effective writing Strategies, Armed Forces College of Medicine, May 2017
24. Application of R program in pharmacoeconomics. 57357 Cancer Children Hospital, September 2017
International conference Participation:
1.I nternational Biotechnology and Research Conference
April 25-27, 2018 Rome, Italy. Evaluation of a Panel of CirRNAs Expression as a Novel Potential Biomarker in Hepatocellular Carcinoma. Kerolos A, Marwa Matboli1, Ayman El-Sayed Shafei, Ahmed M Ashry, Kamal M Kamal3, Mohammed Ali Agag3, Ibrahim Reda3, Hana M Abdelzaher3 and Mahmoud A Ali2
2. Clinical Bioinformatics As a novel approach towards better diagnosis & treatment of human diseases. International Conference of Oncology& Urology, Cairo,1-3/May 2017
3. Investigating miRNA-661 and ATG4b mRNA expression as a potential biomarkers for hepatocellular carcinoma. Biotech Congress 2017:Rome 2017
4.Circular RNAs as Novel Player in Hepatocellular Carcinoma: Functional Considerations and Clinical Translation. World Congress on Cancer. May 3-5, 2017, Melia Barajas, Madrid, Spain. MADRID
5.Clinical implication of miRNA-Autophagy Target Gene Association in Hepatocellular Carcinoma. BITs 9th Cancer Congress international conference , Shangahi, China 2016
H index : 17( Scopus:14) total citations :772(scopus:581) RG score:33.22
Workshop and conference Organization:
1. Biomarker Discovery; in Tumor Markers Workshop, ESTMO , Ain Shams Faculty of Medicine, Cairo, 2015
2.Successful Clinical Research example; in Research Methodology Workshop, Armed Forces College of Medicine, June, 2016
3. Lecturer in the Principles of Research Workshop, Armed Forces College of Medicine, July & August 2016
4.Program coordinator for clinical bioinformatics workshop, Armed Forces College of Medicine, May, 2017
Conferences and workshops attended:
• Biochemistry & Molecular Biology “Present & Future’ (Ain Shams Universitty, 2010)
• Recent Advances in Biochemistry and Molecular Biology (Ain Shams University, 2012)
• The 33rd Annual Conference of The Egyptian Society of Haematology (Marriott Hotel, 2012)
• 10th National Conference for Biochemistry & Molecular Biology (Ain Shams University, 2013)
• Updating The Egyptian Tumor Markers Society (Ain Shams University, June 2013)
• Biochem Cairo 2014: Molecular Clinical Biochemistry Updates (Kasr Al-Ainy Faculty of Medicine, 2014)
• Egyptian Society of Biochemistry & Molecular Biology and The Egyptian Society of Tumor Markers Oncology Annual Scientific Conference (Ain Shams University, 2014)
• How To be a Good Tutor in Problem-Solving Sessions (AFCM, 2015)
• 6th international Gastrointestinal, Liver & Uro-oncology Conference, Mena House Hotel, 2017
• 8th IGLUK conference ,Cairo Egypt 2019
• Ain shams university coin nference 2019
• Applying System biology in biomedical research , potential era in precision Medicine in BIGGC 2020
Awards
• Silver Medal for iGEM Egypt team in IGEM competition in Boston, USA, Sharing as instructor (2018)
• Gold Medal for iGEM Egypt team in IGEM competition in Boston, USA, Sharing as instructor for proposal entitled; Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma (2017)
• Bronze medal for IGEM Egypt Team in IGEM competition in Boston, USA, Sharing as secondary PI for proposal entitled; Targeting circular RNA in hepatocellular carcinoma (2016).
• Ain Shams University Award for international Publication
Editorial Board Member
• World journal of biological chemistry(https://www.wjgnet.com/1949-8454/MemberDetail/3808502 )
• Biomedical Reports(https://www.spandidos-publications.com/br/editorial )
• Journal of Medical Biotechnology (https://www.pulsus.com/archives-medical-biotechnology/editorial-board.html )
• Pharmacology and Therapeutic Research Journal
Reviewer in many international journals
• Biomedicine & pharmacotherapy
• DNA and Cell Biology
• Oncotarget
• Clinics in Research in hepatology & gastroenterology
• Tumor biology
• Translational cancer research
• Cancer biomarkers
• Biomed Research International
Marwa Matboli Sayed Mohamed
Position:
1. Acting head of Medical Biochemistry Department and Molecular Biology, Faculty of Medicine, Modern university for technology and information from July 2019 till present.
2. Associate professor Of Medical Biochemistry Department and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt
3. Member of Basic Research Unit, Medical Research Unit, Ain Shams Faculty of Medicine from 2016 till present
4. Coordinator Of Biomedical Research Department, Armed Forces College of medicine from 2016 till 2017
5. Coordinator Of Medical Biochemistry Department and Molecular Biology, Armed Forces College of medicine from 2016 till 2017
Specialty:
Medical Biochemistry Department and Molecular Biology
Scopus ID
https://www.scopus.com/authid/detail.uri?authorId=55920873100
http://orcid.org/0000-0002-6852-3954
Google Scholar ID
https://scholar.google.com.eg/citations?user=clJGV9UAAAAJ&hl=ar
Researchgate ID
https://www.researchgate.net/account.AccountSettings.html
Subspecialty/ special interest:
Activities
1- Sharing as a member in the teamwork for biomarker discovery in cancer leaded by Prof. Dr. Sanaa Eissa Mohammed, Faculty of Medicine, Ain Shams University.
2-Sharing as a member in the teamwork for bionanotechnology research leaded by Prof. Dr. Hassan Mohamed Elazzazy, Science and Technology Research Center, American University in Cairo.
Grants
1- Sharing as CO-Principal investigator in a project entitled; Development of nanoassay for early detection of Bladder Cancer. Ain Shams University project 2014-2015
2-Sharing as CO-Principal investigator in a project entitled; Development of nanoassay for early detection of Diabetic nephropathy. RSGT 6653, STDF 2015-2016
3-Sharing as Principal investigator in a project entitled; Targeting miRNA by medicinal plants to modulate autophagy signaling pathway: A new therapeutic approach of diabetic nephropathy, RSGT 2751, STDF 2015-2016
4- Sharing as CO-Principal investigator in a project entitled; Target-based therapeutic approach towards diabetes mellitus by modifying autophagy Signaling, Special Targeted Call: Health (Call 3), “TC/3/Health/2017, STDF.
5- Sharing as CO-Principal investigator in a project entitled; Exosomes as divine messengers in Breast cancer: Implications for inter-cellular communication, therapy and biomarker development. Basic & Applied Research, STDF 2017
6-Sharing as CO- Principal investigator in a project entitled; Gene editing of lncRNA-associated ceRNAs network: in treating type 2 DM. ASRT JESOR 2017 ,ID:2017-2961.
7- Sharing as CO- Principal investigator in a project entitled; implementation of comprehensive molecular & next generation sequencing- based genetic testing strategy to improve and prevent fatal outcomes of coronary artery disease related to familial hypercholesterolemia. ASRT JESOR 2017 ,ID:2017-
8- Sharing as CO-Principal investigator in a project entitled; Evbaluation of renal damage after PCNL and ESWEL using novel RNA markers, STDF young researcher 2019
9- Sharing as CO-Principal investigator in a project entitled; Targeted approach for Gut Microbiome Manipulation, novel key player in Type 2 Diabetes mellitus Management. ASRT JESOR 2019
10- Sharing as Principal investigator in a project entitled; Evaluating the Clinical Significance of the Nourin-Based RNA Network for the Early Detection of Acute Myocardial Infarction (AMI) Patients. Armed Forced College of Medicine and Nour Heart Diagnostics &Theraputics, USA, 2017.
11- Sharing as a member in FP7 project entitled (Proteomic analysis in breast screening study) during the period between (2010-2012).
Thesis Supervision
Master Thesis
1. Evaluation of non coding RNA expression in acute kidney injury(2018)
2. Evaluation of Minichromosome maintenance complex component 5 (MCM5) and Forkhead box m (FOXm) genes expression in primary breast cancer (2013).
3. Evaluation of microRNA expression in Obesity (2014)
4. Evaluation of long non-coding RNA expression in hepatocellular carcinoma (2014)
5. The discovery of putative urine marker for detection of diabetic nephropathy by integrative mining of public miRNA databases (2014)
6. Evaluation of long non-coding RNA and Autophagy related gene association in Hepatocellular carcinoma
7. Assessment of Non-Coding RNA Expression as a Potential Stem Cell Biomarker in Breast Cancer
8. Identification of Novel Biomarkers that reflect Mitophagy-Apoptosis Interplay within Hepatocellular Carcinoma
9. Integrative Pipeline to Identify Potential Long Non-Coding RNA-Associated Competing Endogenous RNA and Its Implication in Hepatocellular Carcinoma Cells
10. Phytochemical extracts: A Target based therapeutic approach for diabetes mellitus via autophagy signaling Modulation in rat model
PHD supervision
1. The Effect of Ibuprofen Arginate on a Murine Model of Diabetic Neuropathy & study of the possible mechanisms (2013)
2. Evaluation of MicroRNA-210 (miRNA-210) and Protein tyrosine phosphatase, non-receptor type 2 (PTPN2) in Pre-eclampsia (2015)
3. Epigenetic control of autophagy receptors in diabetic nephropathy (2015)
4. Efficacy of phytochemical extracts of rosemary in Head and neck squamous cell carcinoma cell line (2015)
5. Study of the Effect of Resveratrol and Lycopene on Laryngeal Carcinoma Cell Line (2015)
6. Evaluation of diagnostic and therapeutic Roles of Exosomes in Hepatocellular Carcinoma
7. Evaluation of circular RNA network expression in Hepatocellular carcinoma
8. CLINICAL SIGNIFICANCE OF EXOSOMES AND AUTOPHAGY IN HEPATOCELLULAR CARCINOMA
9. The Clinical Relevance of Non-Coding RNAs in Colorectal Cancer.
10. The Potential Effect of Sodium Butyrate (a Histone deacetylaseinhibitor) on Hepatic Autophagy in Carbon Tetrachloride and Concanavalin A induced Liver Fibrosis in BALB/c mice.
11. Emerging ROLE OF EXOSOMES based therapeutics in management of Hepatocellular carcinoma
12. Evaluation of expression of circulating nucleic acid in traumatic spinal cord injuries
13. Assessment of the efficacy of gene editing tool as a promising strategy in management of insulin resistance in type 2 diabetes mellitus
14. Targeting non-coding RNAs with Gene Editing Tool system in hepatocellular carcinoma cell lines
15. Assessment of Cardiprotective Effect of phytochemical extract in ischemic heart is mediated via induction of stem cell proliferation
16. Efficacy of fucoxanthin on head and neck squamous cell carcinoma cell line
17. Transcriptome spectral analysis using hyperspectral imaging for hepatocellular carcinoma detection
18. Immune modulation in management of colorectal cancer
19. Impact of gut microbiota on the epigenetic regulation of Nonalcoholic Steatohepatitis in animal model
20. Exploring the rule of hedgehog signaling in management of non-alcoholic steatohepatitis
Publications
1. Amany Hasanin, Eman Habib, Nesserin El Gayar, Marwa Matboli. Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study. World Journal of Hepatology March 2021
2. Aboughaleb, I.H., Matboli, M., Shawky, S.M., El-Sharkawy, Y.H. Integration of transcriptomes analysis with spectral signature of total RNA for generation of affordable remote sensing of Hepatocellular carcinoma in serum clinical specimens. Heliyon, 2021, 7(3), e06388
3. Matboli, M., Saad, M., Hasanin, A.H., ...Bekhet, M.M., Eissa, S.New insight into the role of isorhamnetin as a regulator of insulin signaling pathway in type 2 diabetes mellitus rat model: Molecular and computational approach. Biomedicine and Pharmacotherapy, 2021, 135, 111176.
4. Hossam, N., Matboli, M., Shehata, H.H., ...Hassan, M.K., Eissa, S.Toll-like receptor immune modulatory role in personalized management of colorectal cancer, review of literature. Expert Review of Precision Medicine and Drug Development, 2020, 5(6), pp. 455–468.
5. Matboli, M., Ibrahim, D., Hasanin, A.H., ...Afifi, A.M., Eissa, S.Epigenetic modulation of autophagy genes linked to diabetic nephropathy by administration of isorhamnetin in Type 2 diabetes mellitus rats Epigenomics, 2021, 13(3), pp. 187–202
6. Maha Saad, Mansour Mohamed Kabash, Aymn El Sayed Shafei …,Marwa Matboli. Microbiome in GIT Cancers: New Frontiers in Personalized Medicine – A Review of Literature. Journal of surgical oncology 2020
1. Salah SMM, Matboli M, Nasser HE, Abdelnaiem IA, Shafei AE, El-Asmer MF.Dysregulation in the expression of (lncRNA-TSIX, TP53INP2 mRNA, miRNA-1283) in spinal cord injury.Genomics. 2020 Sep;112(5):3315-3321. doi: 10.1016/j.ygeno.2020.06.018. Epub 2020 Jun 11.PMID: 32535070
2. Ali HS, Boshra MS, El Meteini MS, Shafei AE, Matboli M. lncRNA- RP11-156p1.3, novel diagnostic and therapeutic targeting via CRISPR/Cas9 editing in hepatocellular carcinoma.Genomics. 2020 Sep;112(5):3306-3314. doi: 10.1016/j.ygeno.2020.06.020. Epub 2020 Jun 13.PMID: 32544548
3. Marwa Matboli ,Eman K Habib, Reham Hussein Mohamed, Amany H Hasanin. Pentoxifylline alleviated cardiac injury via modulating the cardiac expression of lncRNA-00654-miR-133a-SOX5 mRNA in the rat model of ischemia-reperfusion. Biomedicine and pharmacotherapy 2020. DOI: 10.1016/j.biopha.2020.109842
1. Rashed WM, Hamza MM, Matboli M, Salem SI. MicroRNA as a prognostic biomarker for survival in childhood acute lymphoblastic leukemia: a systematic review.Cancer Metastasis Rev. 2019 Dec 5. doi: 10.1007/s10555-019-09826-0. [Epub ahead of print] Review.PMID: 31807971.
2. AH Hasanin, M Matboli, HS Seleem. Hesperidin suppressed hepatic precancerous lesions via modulation of exophagy in rats. Journal of cellular biochemistry 121 (2), 1295-1306.
3. Mariam Ezzat Labib, Marwa Matboli*, Hanaa El-Tayeb Nasser, Ahmed Hassan Fawzi El-Tawdi, Eman K. Habib, Randa Ali-LabibEXTRACELLULAR VESICLES miR-1298 and lncRNA-RP11-583F2.2 EXPRESSION in HEPATOCELLULAR CARCINOMA. Current Genomics.DOI : 10.2174/1389202920666191210111849
4. Marwa Matboli*, Ayman E. Shafei, Sara H.A. Agwa, Sherif Sammir Elzahy, Ahmed K. Anwar, Amr R. Mansour, Ahmed I. Gaber, Ali E.A. Said, Paula Lwis, Marwa Hamdy. Identification of novel molecular network expression in Acute Myocardial Infarction. Current Genomics Volume 20 , Issue 5 , 2019.DOI : 10.2174/1389202920666190820142043
5. El-Shal AS, Matboli M, Abdelaziz AM, Morsy AA, Abdelbary EH. Role of a novel circulatory RNA-based biomarker panel expression in ovarian cancer.IUBMB Life. 2019 Dec;71(12):2031-2047. doi: 10.1002/iub.2153. Epub 2019 Sep 13.PMID: 31520466.
6. Matboli M, Shafei AE, Ali MA, El-Din Ahmed TS, Naser M, Abdel-Rahman T, Anber N, Ali M. Role of extracellular LncRNA-SNHG14/miRNA-3940-5p/NAP12 mRNA in colorectal cancer.Arch Physiol Biochem. 2019 Aug 9:1-7. doi: 10.1080/13813455.2019.1650070. [Epub ahead of print].PMID: 31397210.
7. Salem AM, Ragheb AS, Hegazy MGA, Matboli M, Eissa S. Caffeic Acid Modulates miR-636 Expression in Diabetic Nephropathy Rats.Indian J Clin Biochem. 2019 Jul;34(3):296-303. doi: 10.1007/s12291-018-0743-0. Epub 2018 Feb 26.PMID: 31391719
8. Ihab S. Abd El-Hamid *, Yara Y. Mouselhy, Marwa M. El-Shafei, Marwa M. Sayed, Aly F. Mohamed, Doaa B. Farag. COX-2 Docking Structural Analysis with Phytochemical Extracts of Rosemary: A Possible Cytotoxicity on Head and Neck Squamous Cell Carcinoma Cell Line (HEp-2). Anti-Cancer Agents in Medicinal Chemistry. DOI : 10.2174/1871520619666190618121706
9. Habieb A, Matboli M, El-Tayeb H, El-Asmar F. Potential role of lncRNA-TSIX, miR-548-a-3p, and SOGA1 mRNA in the diagnosis of hepatocellular carcinoma. Mol Biol Rep. 2019 Apr 19. doi: 10.1007/s11033-019-04810-x. [Epub ahead of print] Erratum in: Mol Biol Rep. 2019 May 2;PMID: 31004302
10. Matboli M, ElGwad AA, Hasanin AH, El-Tawdi A, Habib EK, Elmansy RA, Ibrahim D, Shehata H, Tash F.Pantoprazole attenuates tumorigenesis via inhibition of exosomal secretion in a rat model of hepatic precancerous lesion induced by diethylnitrosamine and 2-acetamidofluorene.J Cell Biochem. 2019 Apr 22. doi: 10.1002/jcb.28757.
11. Eissa S, Safwat M, Matboli M, Zaghloul A, El-Sawalhi M, Shaheen A.Measurement of Urinary Level of a Specific Competing endogenous RNA network (FOS and RCAN mRNA/ miR-324-5p, miR-4738-3p, /lncRNA miR-497-HG) Enables Diagnosis of Bladder Cancer.Urol Oncol. 2019 Apr;37(4):292.e19-292.e27. doi: 10.1016/j.urolonc.2018.12.024. Epub 2019 Jan 14. PMID: 30654976
12. Matboli M, Shafei AE,Ali MA, et al. circRNAs (hsa_circ_00156, hsa_circ000224, and hsa_circ _000520) are novel potential biomarkers in hepatocellular carcinoma. J Cell Biochem. 2018;1‐14.https://doi.org/10.1002/jcb.28045
13. Matboli M, Shafei AE,Ali MA, et al. Clinical significance of serum DRAM1 mRNA, ARSA mRNA, hsa‐miR‐2053 and lncRNA‐RP1‐86D1.3 axis expression in malignant pleural mesothelioma. J Cell Biochem. 2018;1‐9. https://doi.org/10.1002/jcb.27586
14. Samir N, Matboli M, El-Tayeb H, et al. Competing endogenous RNA network crosstalk reveals novel molecular markers I colorectalcancer.JCellBiochem.2018;119:6869–6881.https://doi.org/10.1002/jcb.26884
15. Abd El‐Gwad A, Matboli M, El‐Tawdi A, et al. Role of exosomal competing endogenous RNA in patients with hepatocellular carcinoma. J Cell Biochem. 2018;119:8600–8610.https://doi.org/10.1002/jcb.27109
16. Matboli M1, Shafei A2, Ali M2, Kamal KM3, Noah M3, Lewis P3, Habashy A3, Ehab M3, Gaber AI3, Abdelzaher Emerging role of nutrition and the non-coding landscape in type 2 diabetes mellitus: A review of literature. Gene. 2018 Oct 30;675:54-61. doi: 10.1016/j.gene.2018.06.082. Epub 2018 Jun 27.
17. Shafei A1, Matboli M1,2, Mostafa E1, Al Sannat S1, Abdelrahman M1, Lewis B1, Muhammad B1, Mohamed S2, Mostafa RM Stop eating plastic, molecular signaling of bisphenol A in breast cancer. Environ Sci Pollut Res Int. 2018 Aug;25(24):23624-23630. doi: 10.1007/s11356-018-2540-y. Epub 2018 Jun 29
18. Nossier AI, Abdelzaher H, Matboli M, Eissa S. Dual approach for the colorimetric determination of unamplified microRNAs by using citrate capped gold nanoparticles.Mikrochim Acta. 2018 Mar 22;185(4):236. doi: 10.1007/s00604-018-2767-9
19. Salem, A.M., Ragheb, A.S., Hegazy, M.G.A., Matboli, M., Eissa, S. Caffeic Acid Modulates miR-636 Expression in Diabetic Nephropathy Rats. 2018 Indian Journal of Clinical Biochemistry
20. Mahmoud A. Ali, Marwa Matboli, Nashwa El-Khazragy, Osama Saber, Sarah El-Nakeep, Hana M. Abdelzaher, Ayman El-Sayed Shafei, Randa Mostafa. Investigating miRNA-661 and ATG4-B mRNA expression as potential biomarkers for hepatocellular carcinoma. Biomarkers in Medicine, In Press
21. Marwa Matboli, Ayman E Shafei, Ahmed EM Azazy, Maged Reda, Nashwa El-Khazragy, Ahmed Aly Nagy, Mahmoud A. Ali, Mohamed Sobhi, Omar Abdel-Rahman. Clinical Evaluation of Circulating miR-548-3p and-20a Expression in Malignant Pleural Mesothelioma Patients. Biomarkers in Medicine, In Press
22. Marwa Matboli, Ahmed EM Azazy, SehamAdel, Miram M Bekhet, Sanaa Eissa. Evaluation of Urinary Autophagy Transcripts Expression in Diabetic Kidney Disease. Journal of Diabetes and Its Complications 2017.
23. Marwa Matboli , Ayman E Shafei , Hanan H Shehata ,Nesreen Nabil ,Nourhan Hossam , Ahmed EM Azazy , ,Ahmed HF.El-Tawdi , Omar Abdel-Rahman. Clinical Significance of miRNA-Autophagy Transcript Expression in Patients with Hepatocellular Carcinoma. Biomarkers in Medicine, In Press.
24. A Shafei, M Matboli, M Ali, Z Nagy, M Reda, M Salah, A Hamdy Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma. bioRxiv, 288381 2018
25. S Mohamed, M Matboli, AES Shafei, H Khalaf, M Ashraf, MS Riad. Non-coding RNAs as key player in stem cell proliferation and differentiation; Potential therapeutic strategies in spinal cord injuries. Journal of Medical 2017 Biotechnology 1 (1)
26. FM Tash, AM Abd-Elgawad, M Matboli, SM Shawky, HH Shehata. Clinico-pathological correlates of MCM5 and FOXM1 expression in primary breast cancer tissues J Pharma Pharma Sci 2016
27. Marwa Matboli, Sanaa Eissa, Doaa Ibrahim, Marwa G.A.Hegazy, Shalabia S. Imam, Eman K Habib. Caffeic Acid Attenuates Diabetic Kidney Disease via Modulation of Autophagy in a High-Fat Diet/Streptozotocin- Induced Diabetic Rat. Sci Rep. 2017 May 23;7(1):2263. doi: 10.1038/s41598-017-02320-z.PMID:28536471
28. Eissa, Sanaa, Marwa Matboli ,Nahla Awad, Yousif Kotb Identification and validation of a novel autophagy gene expression signature for human bladder cancer Patients. TUMOR Biology 2017
29. Mahmoud A Ali, Marwa Matboli, Marwa Tarek, Maged Reda, Kamal M Kamal, Mahmoud Nouh, Ahmed M Ashry, Ahmed Fath El-Bab, Hend A Mesalam, Ayman El-Sayed Shafei, and Omar Abdel-Rahman. Epigenetic regulation of immune checkpoints: another target for cancer immunotherapy? Immunotherapy, January 2017 ,Vol. 9, No. 1 , Pages 99-108 (doi: 10.2217/imt-2016-0111)
30. Adel S, Mansour A, Louka M, Matboli M, Elmekkawi SF, Swelam N. Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia. Gene. 2017 Jan 5;596:105-109. doi: 10.1016/j.gene.2016.10.014. Epub 2016 Oct 13.
31. GM El-Lithy, WM El-Bakly, M Matboli, HA Abd-Alkhalek MayHamza. Prophylactic L-arginine and ibuprofen delays the development of tactile allodynia and suppresses spinal miR-155 in a rat model of diabetic neuropathy.Translational Research 2016.
32. Eissa, Sanaa , Marwa Matboli, Rowaida Aboushahba, Miram M. Bekhet, Yasser Soliman. Urinary exosomal microRNA panel unravels novel biomarkers for diagnosis of type 2 diabetic kidney disease. Journal of Diabetes and Its Complications 2016, Volume 0 , Issue 0.
33. El-Tawdi AH, Matboli M, El-Nakeep S, Azazy AE, Abdel-Rahman OAhmed . Association of long noncoding RNA and c-JUN expression in hepatocellular carcinoma Expert Rev Gastroenterol Hepatol. 2016 May 23. [Epub ahead of print]
34. Matboli M, El-Nakeep S, Hossam N, Habieb A, Azazy AEM, Ebrahim AE, Nagy Z, Abdel-Rahman O. Exploring the role of molecular biomarkers as a potential weapon against gastric cancer: A review of the literature. World J Gastroenterol 2016; 22(26): 5896-5908 Available from: URL: http://www.wjgnet.com/1007-9327/full/v22/i26/5896.htm DOI: http://dx.doi.
org/10.3748/wjg.v22.i26.5896
35. Sanaa Eissa, Marwa Matboli, Miram M. Bekhet .Clinical verification of a novel urinary microRNA panel: 133b, -342 and -30 as biomarkers for diabetic nephropathy identified by bioinformatics analysis. Biomedicine & Pharmacotherapy, Volume 83, Issue null, Pages 92-99
36. Ahmed HF.El-Tawdi, Marwa Matboli, Hanan H Shehata, Tash FM, Nashwa El-Khazragy, Ahmed EM Azazy,Omar Abdel-Rahman. Evaluation of Circulatory RNA Based Biomarker Panel in Hepatocellular Carcinoma. Molecular Diagnosis & Therapy 2016. In press
37. MM Kamel, M Matboli, M Sallam, IF Montasser, AS Saad, AHF El-Tawdi. Investigation of long noncoding RNAs expression profile as potential serum biomarkers in patients with hepatocellular carcinoma. Transl Res. 2016 Jan 7.
38. Eissa S, Marwa Matboli, Nada O.E. Essawy, Mahmod Shehta,Youssef M.Kotb. Rapid Detection of Urinary Long Non-Coding RNA Urothelial Carcinoma Associated One Using a PCR-Free Nanoparticle-Based Assay. Biomarkers J 2015.
39. Eissa S, Matboli M, Shawky SM, Essawy NO. Urine biomarkers of Schistosomiais and its associated bladder cancer. Expert review of anti-infective therapy j 2015.
40. S Eissa, M Matboli, A Sharawy, F El-Sharkawi. Prognostic and biological significance of microRNA-221 in breast cancer. Gene 574 (1), 163-167.
41. Eissa S, Matboli M, Hegazy MG, Kotb YM, Essawy NO. Evaluation of urinary microRNA panel in bladder cancer diagnosis: relation to bilharziasis. Transl Res. 2015 Jan 7. pii: S1931-5244(15)00003-1. doi: 10.1016/j.trsl.2014.12.008. [Epub ahead of print] PMID: 25620614
42. Eissa S, Matboli M, Shehata HH, Essawy NO.MicroRNA-10b and minichromosome maintenance complex component 5 gene as prognostic biomarkers in breast cancer. Tumour Biol. 2015 Jan 18. [Epub ahead of print].PMID: 25596707
43. S Eissa, M Matboli, NOE Essawy, YM Kotb. Integrative fun ctional genetic-epigenetic approach for selecting genes as urine biomarkers for bladder cancer diagnosis.Tumor Biology 36 (12), 9545-9552
44. Eissa S, Matboli M, Shehata HH. Breast tissue-based microRNA panel highlights microRNA-23a and selected target genes as putative biomarkers for breast cancer. Transl Res. 2015 Mar;165(3):417-27. doi: 10.1016/j.trsl.2014.10.001. Epub 2014 Oct 31.PMID: 25445205
45. Eissa S, Azzazy HM, Matboli M, Shawky SM, Said H, Anous FA. The prognostic value of histidine-rich glycoprotein RNA in breast tissue using unmodified gold nanoparticles assay. Appl Biochem Biotechnol. 2014 Sep;174(2):751-61. doi: 10.1007/s12010-014-1085-x. PMID: 25091325
46. Matboli M, Eissa S, Said H. Evaluation of histidine-rich glycoprotein tissue RNA and serum protein as novel markers for breast cancer. Med Oncol. 2014 Apr;31(4):897. doi: 10.1007/s12032-014-0897-4. Epub 2014 Feb 25.
47. Eissa S, Matboli M, Mansour A, Mohamed S, Awad N, Kotb YM. Evaluation of urinary HURP mRNA as a marker for detection of bladder cancer: relation to bilharziasis. Med Oncol. 2014 Feb;31(2):804. doi: 10.1007/s12032-013-0804-4. Epub 2013 Dec 28.
48. Eissa S, Shawky SM, Matboli M, Mohamed S, Azzazy HM. Direct detection of unamplified hepatoma upregulated protein RNA in urine using gold nanoparticles for bladder cancer diagnosis. Clin Biochem. 2014 Jan;47(1-2):104-10. doi: 10.1016/j.clinbiochem.2013.10.022. Epub 2013 Oct 29.
49. Matboli M, Eissa S. Integrated technologies in the post-genomic era for discovery of bladder cancer urinary markers. World J Clin Urol 2013 November 24; 2(3): 20-31 .ISSN 2219-2816 (online
50. Sanaa Eissa, Marwa Matboli, Randa Ali-Labib. Apoptosis Inhibitory Gene in Bladder Cancer Diagnosis: Molecular Screening for Bladder Cancer Project PI: Sanaa Eissa Ain Shams Faculty of Medicine ., 2/2012; LAP Lambert Academic Publishing AG & Co KG., ISBN: 9783846586266.
Patency
ELGEBALY SALWA AHMED, SAYED and MARWA MATBOLI .A Novel Autophagy-Related Nourin Gene-Based RNA Network as Early Biomarkers for Cardiac Patients. Grant US-10895572-B2 - Published 2021-01-19 Granted 2021-01-19 Priority 2018-06-18
Family: 6
1-
ELGEBALY SALWA AHMED, SAYED and MARWA MATBOLI . Application WO-2020148589-A1, EARLY BIOMARKERS FOR CARDIAC PATIENTS. Original Assignee :NOUR HEART INC .Legal status Granted
3-Rapid nanoassay for detection of miRNA in urine. ASERT 1631-2017.ID- 16252402
4- Transcriptome spectral analysis using hyperspectral imaging for hepatocellular carcinoma detection. ASERT 1561-2019.
Degrees:
1. MD in Medical Biochemistry and Molecular Biology ,November 2012
Thesis: Proteomic Analysis in Breast Screening Study
Grade: GPA:3.12
Faculty: Faculty of Medicine, Ain Shams University
2. Attached as academic visitor Sant George University of Central London during the period (2010-2012).
3. MSc in Medical Biochemistry, May 2009
Thesis: Detection of mRNA of Apoptosis Inhibition Gene in Urine of Bladder Cancer
Grade: Excellent
Faculty: Faculty of Medicine, Ain Shams University
3-M.B, B.ch in Medicine , December 2002
Grade: Excellent
Faculty: Faculty of Medicine, Ain Shams University
Training:
1. Computer Programs, Faculty of Computer and Bioinformatics, Ain Shams University 2004.
2. Effective Teaching in FLDP 2009
3. Student Assessment, Quality Assurance Unit , Faculty of Medicine ,Ain Shams University ,June 2010
4. How To make Scientific Research in Community Department, Ain Shams University ,2009.
5. Proteomic workshop and sample processing., Saint George University., London ,August ,2010.
6. Maldi/TOF mass spectrometer training and its application in biomarker ,Southampton University , August ,2010.
7. Proteomic analysis in biomarker discovery ,Clinical pathology Department ,Alexandria University ,February 2011.
8. Proteomic analaysis in breast cancer screening workshop .,Biomedical Academy of Athens , 2011.
9. Interactive education., Quality Assurance Unit , Faculty of Medicine ,Ain Shams University ,May 2011
10. Stem cell workshop, biochemistry department, Faculty of Medicine ,Cairo University ,May 2012.
11. Financial & Legal Aspects in College Work, Faculty & Leadership Development Center, Ain Shams University, September 2013
12. Local and international competitive research projects, Faculty & Leadership Development Center, Ain Shams University, August 2014.
13. Teaching methodology, Armed Force faculty of medicine,2014
14. Student Centered Learning in Medical Education, Armed Force faculty of medicine, August 2014
15. Problem-Based Learning in Medical Education, Armed Force faculty of medicine, March 2015
16. Technology in Teaching, Faculty & Leadership Development Center, Ain Shams University, August 2015
17. Constructing Clinical Scenarios in Medical Education, Armed Forces College of Medicine, August 2015.
18. Practical & Online electronic courses, Medical Biochemistry Department, Ain Shams University, 2015-2016
19. Research methodology. Armed Force faculty of medicine, May 2016
20. Researcher Connect Course, British Council in Egypt, February 2017
21. Communicative Presentation Skills by The British University in Egypt, Armed Forces College of Medicine, April 2017.
22. Navigating peer-review workshop, Armed Forces College of Medicine, May 2017.
23. Effective writing Strategies, Armed Forces College of Medicine, May 2017
24. Application of R program in pharmacoeconomics. 57357 Cancer Children Hospital, September 2017
International conference Participation:
1.I nternational Biotechnology and Research Conference
April 25-27, 2018 Rome, Italy. Evaluation of a Panel of CirRNAs Expression as a Novel Potential Biomarker in Hepatocellular Carcinoma. Kerolos A, Marwa Matboli1, Ayman El-Sayed Shafei, Ahmed M Ashry, Kamal M Kamal3, Mohammed Ali Agag3, Ibrahim Reda3, Hana M Abdelzaher3 and Mahmoud A Ali2
2. Clinical Bioinformatics As a novel approach towards better diagnosis & treatment of human diseases. International Conference of Oncology& Urology, Cairo,1-3/May 2017
3. Investigating miRNA-661 and ATG4b mRNA expression as a potential biomarkers for hepatocellular carcinoma. Biotech Congress 2017:Rome 2017
4.Circular RNAs as Novel Player in Hepatocellular Carcinoma: Functional Considerations and Clinical Translation. World Congress on Cancer. May 3-5, 2017, Melia Barajas, Madrid, Spain. MADRID
5.Clinical implication of miRNA-Autophagy Target Gene Association in Hepatocellular Carcinoma. BITs 9th Cancer Congress international conference , Shangahi, China 2016
H index : 17( Scopus:14) total citations :772(scopus:581) RG score:33.22
Workshop and conference Organization:
1. Biomarker Discovery; in Tumor Markers Workshop, ESTMO , Ain Shams Faculty of Medicine, Cairo, 2015
2.Successful Clinical Research example; in Research Methodology Workshop, Armed Forces College of Medicine, June, 2016
3. Lecturer in the Principles of Research Workshop, Armed Forces College of Medicine, July & August 2016
4.Program coordinator for clinical bioinformatics workshop, Armed Forces College of Medicine, May, 2017
Conferences and workshops attended:
• Biochemistry & Molecular Biology “Present & Future’ (Ain Shams Universitty, 2010)
• Recent Advances in Biochemistry and Molecular Biology (Ain Shams University, 2012)
• The 33rd Annual Conference of The Egyptian Society of Haematology (Marriott Hotel, 2012)
• 10th National Conference for Biochemistry & Molecular Biology (Ain Shams University, 2013)
• Updating The Egyptian Tumor Markers Society (Ain Shams University, June 2013)
• Biochem Cairo 2014: Molecular Clinical Biochemistry Updates (Kasr Al-Ainy Faculty of Medicine, 2014)
• Egyptian Society of Biochemistry & Molecular Biology and The Egyptian Society of Tumor Markers Oncology Annual Scientific Conference (Ain Shams University, 2014)
• How To be a Good Tutor in Problem-Solving Sessions (AFCM, 2015)
• 6th international Gastrointestinal, Liver & Uro-oncology Conference, Mena House Hotel, 2017
• 8th IGLUK conference ,Cairo Egypt 2019
• Ain shams university coin nference 2019
• Applying System biology in biomedical research , potential era in precision Medicine in BIGGC 2020
Awards
• Silver Medal for iGEM Egypt team in IGEM competition in Boston, USA, Sharing as instructor (2018)
• Gold Medal for iGEM Egypt team in IGEM competition in Boston, USA, Sharing as instructor for proposal entitled; Competing endogenous RNA network: Potential entrants to gene editing in Hepatocellular Carcinoma (2017)
• Bronze medal for IGEM Egypt Team in IGEM competition in Boston, USA, Sharing as secondary PI for proposal entitled; Targeting circular RNA in hepatocellular carcinoma (2016).
• Ain Shams University Award for international Publication
Editorial Board Member
• World journal of biological chemistry(https://www.wjgnet.com/1949-8454/MemberDetail/3808502 )
• Biomedical Reports(https://www.spandidos-publications.com/br/editorial )
• Journal of Medical Biotechnology (https://www.pulsus.com/archives-medical-biotechnology/editorial-board.html )
• Pharmacology and Therapeutic Research Journal
Reviewer in many international journals
• Biomedicine & pharmacotherapy
• DNA and Cell Biology
• Oncotarget
• Clinics in Research in hepatology & gastroenterology
• Tumor biology
• Translational cancer research
• Cancer biomarkers
• Biomed Research International
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