Reactions of 5-bromo-4,6-dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile with organophosphorus reagents
Abdel-Malek H.; M. S. Salem; Boulos L.;
Abstract
The reaction of 5-bromo-4,6-dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile (1) with phosphorus ylides 2a,b afforded the new phosphonium ylides 7a,b. Wittig - Honer reagent 3 reacts with 1 to give the olefinic product 8. On the other hand, the dimeric compound 9 and the alkylated products 10, 11 were isolated from the reaction of 1 with dialkyl phosphite 4, trialkyl phosphite 5 and tris(dimethylamino) phosphine 6. Possible reaction mechanisms are considered, and the structural assignments are based on analytical and spectroscopic evidence.
Other data
| Title | Reactions of 5-bromo-4,6-dimethyl-2-thioxo-1,2-dihydropyridine-3-carbonitrile with organophosphorus reagents | Authors | Abdel-Malek H. ; M. S. Salem ; Boulos L. | Issue Date | 1-Dec-2012 | Journal | Life Science Journal | DOI | 1 https://api.elsevier.com/content/abstract/scopus_id/84874864958 695 9 |
Scopus ID | 2-s2.0-84874864958 |
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