Antioxidant and anti-cancer effect of Egyptian and European pumpkin seed oil
Al-Okbi S.; Mohamed D.; Kandil E.; Ahmed, Emad; Mohammed S.;
Abstract
The aim of the present research was to study the anti-cancer and in-vitro antioxidant activity of Egyptian and European pumpkin seed oil (PSO). The anti-cancer effect of the oils was examined in different human cancer cell lines represented by HepG-2 (liver cancer cells), MCF-7 (breast cancer cells) and Caco-2 (colon cancer cells). Results clarified that Egyptian PSO has significant higher antioxidant activity than the European (105.1 �8.3 and85.5�7.6, p < 0.05; respectively). The two oils could inhibit colon cancer cell line with an IC50value of 0.483mg. Egyptian oil showed higher anti-cancer activity than the European towards liver cancer cell while the Egyptian oil had lower activity towards breast cancer cell compared with the European oil.
Other data
Title | Antioxidant and anti-cancer effect of Egyptian and European pumpkin seed oil | Authors | Al-Okbi S. ; Mohamed D. ; Kandil E. ; Ahmed, Emad ; Mohammed S. | Issue Date | 1-Sep-2016 | Journal | Research Journal of Pharmaceutical, Biological and Chemical Sciences | DOI | 5 https://api.elsevier.com/content/abstract/scopus_id/84987720599 574 7 |
Scopus ID | 2-s2.0-84987720599 |
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