Antileishmanial, Antimicrobial and Antifungal Activities of Some New Aryl Azomethines
Yasser M. S. A. Al- Kahraman; Hassan M. F. Madkour; Dildar Ali; Masoom Yasinzai;
Abstract
A series of eighteen azomethines has been synthesized by the reaction of appropriate primary aromatic amines with aryl and/or heteroaryl carboxaldehydes. The synthesized azomethines have been evaluated for their in vitro antileishmanial, antibacterial and antifungal activities. The results revealed some antifungal activity of most of the synthesized compounds, whereas the antileishmaniasis activity results highlighted that all synthesized azomethines inhibited parasite growth and most of them showed highly potent action towards Leishmania major promastigotes. No remarkable bactericidal activities were observed. © 2010 by the authors.
Other data
| Title | Antileishmanial, Antimicrobial and Antifungal Activities of Some New Aryl Azomethines | Authors | Yasser M. S. A. Al- Kahraman ; Hassan M. F. Madkour ; Dildar Ali ; Masoom Yasinzai | Keywords | Antibacterial activity;Antifungal activity;Antileishmanial activity;Azomethines;Hetaryl carboxyladehyes;Primary aromatic amines | Issue Date | 1-Feb-2010 | Journal | Molecules | Volume | 15 | Issue | 2 | ISSN | 1420-3049 | DOI | 10.3390/molecules15020660 | PubMed ID | 20335936 | Scopus ID | 2-s2.0-77649230502 |
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