Copper (II)-surfactant complex and its nano analog as potential antitumor agents
Badawi A.; Zakhary N.; Morsy S.; Mahmoud Shouckry, Gilane Mohamed Sabry; Mohamed M.; Mousa A.;
Abstract
The in vitro anticancer activity of copper cetyl trimethyl ammonium bromide (Cu-CTAB)-loaded cyclodextrin nanoparticles on Ehrlich ascites carcinoma (EAC), colon cancer cells (HCT 116), liver cancer cells (HepG-2), breast cancer cells (MCF-7), and cervix cancer cells (Hela) was investigated using MTT due assay. Cyclodextrin nanoparticles loaded with Cu-CTAB exerted in vitro anticancer activity against the previous human cancer cell lines comparable to the activity of free non-entrapped in nanoparticles macro-particle Cu-CTAB. The nano analog was synthesized by physical loading using grinding with ball mill. The ratio between Cu-CTAB and cyclodextrin oligosaccharide was 1 Cu-CTAB: 3 cyclodextrin. The particle size of the nano derivative was determined using the transmitted electron microscope (TEM). © Taylor & Francis Group, LLC.
Other data
| Title | Copper (II)-surfactant complex and its nano analog as potential antitumor agents | Authors | Badawi A. ; Zakhary N. ; Morsy S. ; Mahmoud Shouckry, Gilane Mohamed Sabry ; Mohamed M. ; Mousa A. | Issue Date | 1-Oct-2009 | Publisher | TAYLOR & FRANCIS INC | Journal | Journal of Dispersion Science and Technology | DOI | 1303 9 1309 https://api.elsevier.com/content/abstract/scopus_id/70449427624 30 10.1080/01932690902735439 |
Scopus ID | 2-s2.0-70449427624 | Web of science ID | WOS:000270206800009 |
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