A Convenient Synthetic Route of Diethyl (4-Oxo-chromeno[2,3-d]pyrimidin-2(5)-yl)phosphonates
Ali, Tarik E.; Assiri, Mohammed A.; Hassanin, Noha M.; Yahia, I. S.; Mai S.A. Hussien;
Abstract
Novel diethyl (4-oxo-3,4-dihydro-2H-chromeno[2,3-d]pyrimidin-2-yl)phosphonate as two enantiomers and diethyl (4-oxo-1,5-dihydro-4H-chromeno[2,3-d]pyrimidin-5-yl) phosphonate were obtained in easy procedure via reaction of 2-imino-2H-chromene-3-carboxamide, dimethylformamide dimethyl-acetal, and diethyl phosphite in a simple one pot. Possible reaction mechanisms were proposed. The structures of the obtained products were confirmed by elemental analyses and spectral tools.
Other data
| Title | A Convenient Synthetic Route of Diethyl (4-Oxo-chromeno[2,3-d]pyrimidin-2(5)-yl)phosphonates | Authors | Ali, Tarik E.; Assiri, Mohammed A.; Hassanin, Noha M.; Yahia, I. S.; Mai S.A. Hussien | Keywords | BIOLOGICAL EVALUATION;ACID-DERIVATIVES;ALDEHYDES | Issue Date | 1-May-2019 | Publisher | WILEY | Journal | Journal of Heterocyclic Chemistry | ISSN | 0022152X | DOI | 10.1002/jhet.3550 | Scopus ID | 2-s2.0-85063582691 | Web of science ID | WOS:000467583400024 |
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