Relative expression and prognostic significance of forkhead box P3 in childhood B-cell acute lymphoblastic leukemia
Abdelhafeez, Hossam El-Din A; Abdel Hamid, Fatma F; Hassan, Naglaa M; Assem, Magda M; Soliman, Ahmed F;
Abstract
Despite the favorable survival rates of childhood B-cell acute lymphoblastic leukemia (B-ALL), a significant number of patients present a dismal prognosis. Forkhead box P3 (FOXP3), a marker of regulatory T cells, functions as a transcription factor involved in immune cell regulation, and its expression correlates with prognosis in many malignancies. Therefore, this study aimed to assess the relative gene expression level of FOXP3 in childhood B-ALL and to detect its prognostic utility.
Other data
| Title | Relative expression and prognostic significance of forkhead box P3 in childhood B-cell acute lymphoblastic leukemia | Authors | Abdelhafeez, Hossam El-Din A; Abdel Hamid, Fatma F; Hassan, Naglaa M; Assem, Magda M; Soliman, Ahmed F | Keywords | childhood B-cell acute lymphoblastic leukemia (childhood B-ALL);forkhead box P3 (FOXP3);prognosis | Issue Date | 16-Jun-2021 | Journal | Pediatric blood & cancer | ISSN | 1545-5009 1545-5017 |
DOI | 10.1002/pbc.29129 | PubMed ID | 34133057 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.