Regioselective Synthesis of Novel Functionalized Pyrano[2′,3′:4,5]pyrimido[1,6-b][1,2,4,5]triazaphosphepines
Ali, T. E.; Assiri, M. A.; Yahia, I. S.; Zahran, H. Y.; Meselhy, M. H.; Mai S.A. Hussien;
Abstract
Abstract: The reactions of6-acetyl-3-amino-4-imino-7-methyl-5-phenyl-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine with triethyl phosphite and some electrophilicreagents, namely 1,2-dibromoethane, oxalyl chloride, chloroacetyl chloride, andethyl chloroacetate, were studied. These one-pot three-component reactionsregioselectively afforded four new11-acetyl-2-ethoxy-10-methyl-12-phenylpyrano[2′,3′:4,5]pyrimido[1,6-b][1,2,4,5λ5]triazaphosphepin-2-ones in69–73% yields.
Other data
| Title | Regioselective Synthesis of Novel Functionalized Pyrano[2′,3′:4,5]pyrimido[1,6-b][1,2,4,5]triazaphosphepines | Authors | Ali, T. E.; Assiri, M. A.; Yahia, I. S.; Zahran, H. Y.; Meselhy, M. H.; Mai S.A. Hussien | Keywords | pyran;pyrimidine;regioselective;synthesis;triazaphosphepine | Issue Date | 1-Jan-2021 | Publisher | MAIK NAUKA/INTERPERIODICA/SPRINGER | Journal | RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | ISSN | 10704280 | DOI | 10.1134/S1070428021010115 | Scopus ID | 2-s2.0-85101770225 | Web of science ID | WOS:000621823200011 |
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