Single-Crystal Structure and Antimicrobial Activity of Ethyl 3-Amino-1-(4- chlorophenyl)-9-hydroxy1H-benzo[f]chromene-2-carboxylate Combined with Ethyl alpha-Cyano-4-chlorocinnamate
Heba Kamal Abd El-Mawgoud; H. A. M. Radwan; F. El-Mariah; A. M. El-Agrody; A. E. Amr; M. A. Al-Omar; H. A. Ghabbour;
Abstract
The titles compounds ethyl 3-amino-1-(4-chlorophenyl)-9-hydroxy-1H-benzo[f]-chromene-2-carboxylate
and ethyl 3-amino-1-(4-chlorophenyl)-9-hydroxy-1H-benzo[f]-chromene-2-carboxylate-ethyl α-cyano-4-
chlorocinnamate complex were synthesized via the reaction of naphthalene-2,7-diol with a mixture of 4-chlorobenzaldehde
with ethyl cyanoacetate or ethyl α-cyano-4-chlorocinnamate, respectively. Structures of the synthesized
compounds were elucidated from spectral data: IR, NMR, MS, and X-ray single crystal analysis. The crystalline
monoclinic molecular structure of C22H18ClNO4·C12H10ClNO2 was characterized by the following data P21/c,
a = 8.7426 (4) Å, b = 13.9342 (7) Å, c = 25.4961 (13) Å, β = 90.824 (2)°, V = 3105.6 (3) Å3, Z = 4.
and ethyl 3-amino-1-(4-chlorophenyl)-9-hydroxy-1H-benzo[f]-chromene-2-carboxylate-ethyl α-cyano-4-
chlorocinnamate complex were synthesized via the reaction of naphthalene-2,7-diol with a mixture of 4-chlorobenzaldehde
with ethyl cyanoacetate or ethyl α-cyano-4-chlorocinnamate, respectively. Structures of the synthesized
compounds were elucidated from spectral data: IR, NMR, MS, and X-ray single crystal analysis. The crystalline
monoclinic molecular structure of C22H18ClNO4·C12H10ClNO2 was characterized by the following data P21/c,
a = 8.7426 (4) Å, b = 13.9342 (7) Å, c = 25.4961 (13) Å, β = 90.824 (2)°, V = 3105.6 (3) Å3, Z = 4.
Other data
Title | Single-Crystal Structure and Antimicrobial Activity of Ethyl 3-Amino-1-(4- chlorophenyl)-9-hydroxy1H-benzo[f]chromene-2-carboxylate Combined with Ethyl alpha-Cyano-4-chlorocinnamate | Authors | Heba Kamal Abd El-Mawgoud ; H. A. M. Radwan; F. El-Mariah; A. M. El-Agrody; A. E. Amr; M. A. Al-Omar; H. A. Ghabbour | Keywords | naphthalene-2,7-diol;X-ray analysis;β-enaminoester complex;β-enaminoester | Issue Date | Mar-2020 | Publisher | Pleiades Publishing, Ltd. | Journal | Russian Journal of General Chemistry | Volume | 90 | Issue | 2 | Start page | 299 | End page | 304 | DOI | 10.1134/S107036322002022X |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.