Validated chemometrics-assisted spectrophotometric methods for simultaneous determination of bisphenol-A-diglycidyl ether and some of its reaction products in canned foods in the Egyptian market
El-Kosasy, Amira M; Miriam Farid Ayad Ayad; Mabrouk, Ola M;
Abstract
Two multivariate calibration methods, namely principal component regression (PCR) and partial least squares (PLS-2) have been developed, validated and compared for the simultaneous determination of bisphenol-A-diglycidyl ether (BADGE) and some of its reaction products, including BADGE·HCl·H2O, BADGE·H2O and BADGE·2HCl. Chemometrics allowed rapid, accurate and precise simultaneous quantification of the analytes of interest which was not possible by other spectrophotometric methods due to their severe spectral overlap. PCR and PLS-2 techniques successfully quantified BADGE, BADGE·HCl·H2O, BADGE·H2O and BADGE·2HCl in the ranges of 1.4-3.4, 1-5, 1-4.2 and 1-7 μg mL-1, respectively. The constructed models were validated according to the International Conference on Harmonization guidelines and successfully applied for the determination of these compounds in pure form, laboratory prepared mixtures and in various types of canned foods following the limits and regulations of the European Union (EU) where satisfactory recovery results were obtained.
Other data
Title | Validated chemometrics-assisted spectrophotometric methods for simultaneous determination of bisphenol-A-diglycidyl ether and some of its reaction products in canned foods in the Egyptian market | Authors | El-Kosasy, Amira M; Miriam Farid Ayad Ayad ; Mabrouk, Ola M | Keywords | Food contact materials;Bisphenols;Canned foods;Principal component regression;Partial least squares;Multivariate calibration | Issue Date | 5-Oct-2018 | Publisher | Elsevier | Journal | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy | Volume | 203 | Start page | 443 | End page | 449 | ISSN | 13861425 | DOI | 10.1016/j.saa.2018.05.120 | PubMed ID | 29894958 | Scopus ID | 2-s2.0-85048222331 | Web of science ID | WOS:000437816000055 |
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