Study of the Reactivity of 6,8-Dimethyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde Towards Amino-6-oxopyridine-3-carboxylate Derivatives

Metwally El-Shaaer, Hafez; Abd-Elmonem, WR; Ibrahim, SS; Ibrahim, CG;

Abstract


The condensation reactions of 6,8-dimethyl-4-oxo-4H-1-benzopyran-3- carboxaldehyde (1) with equimolar amounts of ethyl 2-amino-4-(4-chlorophenyl)-5- cyano-1-[(5,6-diphenyl-1,2,4-triazin-3-yl)amino]-6-oxo-1,6-dihydropyridine-3- carboxylate (2) at different reaction conditions gave different chromanone and chromenone products 3, 4, 5. Also, the condensation reactions of compound 1 with ethyl 5-cyano-1,2-diamino-4-(3-nitrophenyl)-6-oxo-1,6-dihydropyridine-3- carboxylate (6) in absolute ethanol, dry benzene, acetic acid, and/or dry xylene gave a variety of products 7, 8, 9, 10 depending on the solvent used. © 2014 HeteroCorporation.


Other data

Title Study of the Reactivity of 6,8-Dimethyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde Towards Amino-6-oxopyridine-3-carboxylate Derivatives
Authors Metwally El-Shaaer, Hafez ; Abd-Elmonem, WR; Ibrahim, SS; Ibrahim, CG
Keywords HETEROCYCLIC-SYSTEMS;DNA-BINDING PROPERTIES;LN(III) COMPLEXES;CYTOTOXIC ACTIVITY
Issue Date 2014
Publisher WILEY
Journal Journal of Heterocyclic Chemistry 
ISSN 0022-152X
DOI 10.1002/jhet.1919
Scopus ID 2-s2.0-84907423635
Web of science ID WOS:000341631500023

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