Insights on monkeypox disease and its recent outbreak with evidence of nonsynonymous missense mutation
Elhusseiny, Shaza M; Bebawy, Abraam S; Saad, Bishoy T; Aboshanab K. M.;
Abstract
The 2022 monkeypox outbreak has created a new global health threat and pandemic. Monkeypox virus is a descendant of the genus Orthopoxvirus, producing a febrile skin rash disease in humans. Monkeypox is zoonotic transmitted and transmitted from human to human in several ways. Even though this disease is self-limited, it creates important community health worries due to its inconvenience and widespread complications. Herein, we discussed the up-to-date current situation of monkeypox regarding its epidemiology, clinical manifestations, current in-use therapeutics, necessary protective measures, and response to potential occurrences considering the recent pandemic. Also, in this review, a comparative genomic analysis of the recent circulating strains that have been recovered from various countries including, Egypt, USA, Spain, Japan and South Africa has been investigated.
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Title | Insights on monkeypox disease and its recent outbreak with evidence of nonsynonymous missense mutation | Authors | Elhusseiny, Shaza M; Bebawy, Abraam S; Saad, Bishoy T; Aboshanab K. M. | Keywords | anti-virals;epidemiology;monkeypox virus;orthopoxviruses | Issue Date | Aug-2023 | Journal | Future science OA | ISSN | 2056-5623 | DOI | 10.2144/fsoa-2023-0048 | PubMed ID | 37485445 | Scopus ID | 2-s2.0-85166411550 |
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