Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars
Youssef, Reem A; Sakr, Masarra M; Shebl, Rania I; Saad, Bishoy T; Aboshanab, Khaled;
Abstract
Salmonella infections continue to be one of the essential public health issues threatening millions of people. With the increasing occurrence of resistance against conventionally used antibiotics, the search for alternatives has become crucial. In this study, we aimed to isolate, characterize, and evaluate two lytic bacteriophages against clinically isolated multidrug-resistant (MDR) Salmonella serovars.
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Title | Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars | Authors | Youssef, Reem A; Sakr, Masarra M ; Shebl, Rania I; Saad, Bishoy T; Aboshanab, Khaled | Keywords | Histopathology;Microencapsulation;Multidrug-resistant;Bacteriophage;Salmonella;electron microscopy | Issue Date | 15-Feb-2024 | Journal | Annals of clinical microbiology and antimicrobials | ISSN | 1476-0711 | DOI | 10.1186/s12941-024-00678-3 | PubMed ID | 38360595 | Scopus ID | 2-s2.0-85185236406 |
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