Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars

Youssef, Reem A; Sakr, Masarra M; Shebl, Rania I; Saad, Bishoy T; Aboshanab, Khaled;

Abstract


Salmonella infections continue to be one of the essential public health issues threatening millions of people. With the increasing occurrence of resistance against conventionally used antibiotics, the search for alternatives has become crucial. In this study, we aimed to isolate, characterize, and evaluate two lytic bacteriophages against clinically isolated multidrug-resistant (MDR) Salmonella serovars.


Other data

Title Genomic characterization, in vitro, and preclinical evaluation of two microencapsulated lytic phages VB_ST_E15 and VB_ST_SPNIS2 against clinical multidrug-resistant Salmonella serovars
Authors Youssef, Reem A; Sakr, Masarra M ; Shebl, Rania I; Saad, Bishoy T; Aboshanab, Khaled 
Keywords Histopathology;Microencapsulation;Multidrug-resistant;Bacteriophage;Salmonella;electron microscopy
Issue Date 15-Feb-2024
Journal Annals of clinical microbiology and antimicrobials 
ISSN 1476-0711
DOI 10.1186/s12941-024-00678-3
PubMed ID 38360595
Scopus ID 2-s2.0-85185236406

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