Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate
Kamel, Noha A; Tohamy, Sally T; Alshahrani, Mohammad Y; Aboshanab, Khaled;
Abstract
Multidrug-resistant (MDR) P. aeruginosa is a rising public health concern, challenging the treatment of such a ubiquitous pathogen with monotherapeutic anti-pseudomonal agents. Worryingly, its genome plasticity contributes to the emergence of P. aeruginosa expressing different resistant phenotypes and is now responsible for notable epidemics within hospital settings. Considering this, we aimed to evaluate the synergistic combination of fortimicin with other traditional anti-pseudomonal agents and to analyze the resistome of pan-drug resistant (PDR) isolate.
Other data
| Title | Evaluation of fortimicin antibiotic combinations against MDR Pseudomonas aeruginosa and resistome analysis of a whole genome sequenced pan-drug resistant isolate | Authors | Kamel, Noha A ; Tohamy, Sally T; Alshahrani, Mohammad Y; Aboshanab, Khaled | Keywords | Fortimicin;MDR P. Aeruginosa;PDR P. Aeruginosa;Resistome analysis | Issue Date | 14-May-2024 | Journal | BMC Microbiology | ISSN | 1471-2180 | DOI | 10.1186/s12866-024-03316-2 | PubMed ID | 38745145 | Scopus ID | 2-s2.0-85193041857 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.